We are an academic research group in the Department of Biochemistry and Molecular Medicine at Université de Montréal (UdeM).

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We study the cellular mechanisms that maintain DNA integrity and prevent genomic instability, and we have a particular interest in the family of enzyme known as poly(ADP-ribose) polymerases, or PARPs.

 

We use biochemistry, cell biology, and the powerful tools of structural biology (i.e. X-ray crystallography, small-angle x-ray scattering, and electron microscopy) to address fundamental biological questions.